Interactions between malaria parasites and avian hosts

I use dual RNA-sequencing of birds infected with malaria parasites. Because I'm sequencing the blood, this allows me to analyse not only the transcriptome of the host, but also the transcriptome of the parasite simultaneously. This gives unprecedented opportunity to evaluate real-time interactions between hosts and parasites. 

Publications and manuscripts in this project:

  • Videvall et al. (2015) The Avian Transcriptome Response to Malaria Infection. Molecular Biology and Evolution.
  • Bensch et al. (2016) The genome of Haemoproteus tartakovskyi and its relationship to human malaria parasites. Genome Biology and Evolution.
  • Videvall et al. (2017) The transcriptome of the avian malaria parasite Plasmodium ashfordi displays host-specific gene expression. Molecular Ecology.
  • Hellgren et al. (2017) De novo synthesis of thiamine (vitamin B1) is the ancestral state in Plasmodium parasites - evidence from avian haemosporidians. Parasitology.
  • Videvall. (2018) Plasmodium parasites of birds have the most AT-rich genes of eukaryotes. Microbial Genomics
  • Videvall et al. (2018) Avian transcriptome responses to high- and low-virulent malaria strains
    over the course of infection. Complete manuscript included in thesis. 

The gut microbiome's influence on avian fitness and survival


Ostrich chicks can experience dramatic mortality rates due to disease. The development of a healthy gut microbiome seems to be a crucial step in the first three months of an ostrich.

I use 16S rRNA Illumina MiSeq to characterize the gut microbiome over time and associate its various components with growth and survival.

Publications and manuscripts in this project:

  • Videvall et al. (2017) Direct PCR offers a fast and reliable alternative to conventional DNA isolation methods for  gut microbiomes. mSystems.
  • Videvall et al. (2017) Measuring the gut microbiome in birds: comparison of faecal and cloacal sampling. Molecular Ecology Resources.
  • Videvall et al. (2018) The colonization of gut microbiota during development and its association with growth in ostriches. bioRxiv. 
  • Videvall et al. (2018) Mortality patterns and gut microbiome dysbiosis in juvenile ostriches. Complete manuscript included in thesis. 
  • Videvall et al. Effects of coprophagy on the gut microbiome of juvenile ostriches. In prep

Other research projects

In addition to my PhD work, I'll also briefly mention some of the collaborating projects I'm currently involved in:

  • Expression of MHC genes using different techniques (Anna Drews)
  • Great Reed Warbler genome assembly (Bengt Hansson)
  • Sex-specific gene expression in birds using RNA-sequencing (Sigeman et al. Submitted)

Previous research

  • Transcriptome differences between urban and rural birds - (Watson et al. 2017)
  • Transcriptomics of outcrossing Arabidopsis lyrata - (Videvall et al. 2016)
  • Transcriptomics of the hessian fly - (Andersson et al. 2014)
  • Molecular identification of blood meals in biting midges - (Pettersson et al. 2013)
  • Monitoring butterflies using grid-based sampling - (Videvall et al. 2016)

Future research?

Interested in collaborating, or need someone with bioinformatic knowledge to assist with analyses? Contact me with any inquiries.

All figures on this page have been produced by me. Some might still be unpublished so please do not use them without asking for permission.